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HIV Education > HIV Clinical Updates > Previous Version

This section includes brief bulletins about topics of interest to those involved in the field of HIV resistance.


(Release date: July 13, 2010)

CROI 2010: Resistance Update #6. Decrease prevalence of drug resistance mutations in a large, multisite cohort (2002-2008)

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(Release date: June 28, 2010)

CROI 2010: Resistance Update #5. NA-ACCORD: estimating the prevalence of multidrug resistance in North America.

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(Release date: June 14, 2010)

CROI 2010: Resistance Update #4. Tracking transmitted drug resistance-associated mutations among recent and long-standing HIV infection.

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(Release date: June 1, 2010)

CROI 2010: Resistance Update #3. Is behavioral risk reduction sustained over the long-term?

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(Release date: May 11, 2010)

CROI 2010: Resistance Update #2. Raltegravir genetic resistance patterns in HIV-2 patients.

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(Release date: March 30, 2010)
(Release date: March 30, 2010)

CROI 2010: Resistance Update #1. Resistance-associated mutations to etravirine in non-B HIV-1 subtypes.

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(Release date: November 16, 2009)

An analysis of the relative contributions of specific drugs to virological response.

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(Release date: October 19, 2009)

Correlating virtual phenotype-LM with an independent phenotypic assay (van Houtte et al) and recent enhancements to virco®TYPE HIV-1 analyses (Winters et al).

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(Release date: April 22, 2009)

Nine-year trends in clinically relevant reduced susceptibility of HIV-1 to antiretrovirals.

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HIV9 Meeting Glasgow Scotland (Release date: Jan. 19, 2009)

The failure of some patients to fully respond to antiretroviral treatment regimens despite having viruses predicted as susceptible by genotypic analysis can present a clinical conundrum.

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2008 ICAAC/IDSA Meeting (Release date: Nov. 17, 2008)

Phenotype-based HIV resistance testing provides valuable information to help guide the selection of treatment regimens, particularly in patients with likely resistance to one or more ARVs.

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2008 International HIV Drug Resistance Workshop (Release date: Jul. 14, 2008)

Phenotypic susceptibility to the first generation NNRTIs (efavirenz and nevirapine) is significantly affected by single mutations in the HIV viral genome.

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2008 Euro HIV Drug Resistance Workshop (Release date: Jun. 30, 2008)

The emergence of drug-resistant HIV strains is one of the key factors associated with suboptimal virologic response to antiretroviral therapy.

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News from the 24th Annual Clinical Virology Symposium (Release date: Jun. 2, 2008)

The virco®TYPE HIV-1 v4.2.01 (vT) and the PhenoSense GTTM (PSGT) assays use different methods to account for such mixtures in patient samples undergoing evaluation for antiretroviral drug susceptibility.

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A recent study demonstrates accurate prediction of drug susceptibility from viral genotype (Release date: May 27, 2008)

The VirtualPhenotypeTM-LM is a data-driven linear-regression modeling engine that provides an accurate prediction of the HIV resistance phenotype from the viral genotype.

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News from the 6th European HIV Drug Resistance Workshop (Release date: May 10, 2008)

The interpretation of quantitative phenotypic resistance information via clinical cut-off values on the virco®TYPE HIV-1 report can assist HIV providers in optimizing combination antiretroviral therapy.

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News from the 15th Conference on Retroviruses and Opportunistic Infections (Release date: Mar. 3, 2008)

Etravirine (TMC125), a new next-generation NNRTI, shows antiviral activity in treatment-experienced adult patients with HIV resistant to a NNRTI and other antiretroviral agents.

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News from the 15th Conference on Retroviruses and Opportunistic Infections (Release date: Feb. 18, 2008)

Bart Winters and colleagues from Virco, presented data at the 15th Conference on Retroviruses and Opportunistic Infections on the development of virco®TYPE HIV-1 clinical cut-off values for etravirine based on treatment response data from etravirine phase II/III studies.

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News from the 45th Annual Meeting of the Infectious Diseases Society of America (Release date: Dec. 03, 2007)

Current guidelines recommend the use of resistance tests to optimize the selection of active regimens when initiating or changing antiretroviral therapy.

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News from the 47th Interscience Conference on Antimicrobial Agents and Chemotherapy (Release date: Sep. 26, 2007)

Earlier studies using a limited number of laboratory and clinical isolates demonstrated that the HIV-1 protease mutation I50L confers resistance to atazanavir and susceptibility to other protease inhibitors (PIs).

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News from the 16th International HIV Drug Resistance Workshop (Release date: Sep. 06, 2007)

An important aspect of the development of any system that predicts response to antiretroviral therapy is its validation in a diverse clinical dataset not used for algorithm development.

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News from the 23rd Clinical Virology Symposium (Release date: May. 24, 2007)

Karam Mounzer and colleagues from The Jonathan Lax Treatment Center, in collaboration with Virco, presented a poster at the 23rd Annual Clinical Virology Symposium evaluating concordance of drug-specific resistance in PhenoSense GTTM (PGT) and virco®TYPE HIV-1 (virtual phenotype, VP) and estimated the cost savings associated with introduction of VP assays into a community-based clinic.

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News from the 5th European HIV Drug Resistance Workshop (Release date: May. 17, 2007)

The 5th European HIV Drug Resistance Workshop featured 7 important scientific contributions by researchers at Virco Labs.

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What's New

Virco


These modules are presented in an easy to navigate format and begin with a history of the HIV/AIDS epidemic and current epidemiology.

November 2009
Volume 1, Number 3

Presented by Dr. Rafael E. Campo

A 49-year-old African American male, with a history of IDU, unexpectedly presents to the clinic with viremia and declining CD4 cell count after being lost to follow-up for 2.5 years..

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DHHS Guideline

Updated December 1, 2009 — Antiretroviral Guidelines for Adults and Adolescents: Drug Resistance Testing

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Resistance Quiz

There are currently only two types of HIV drug resistance tests.